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Isoalantolactone inhibits constitutive NF-B activation and induces reactive oxygen species-mediated apoptosis in osteosarcoma U2OS cells through mitochondrial dysfunction

However, many people with fatty liver have other risk factorssuch as metformin use, proton pump inhibitors, or dietary restrictionsthat can independently lead to B12 deficiency, making monitoring important when symptoms or risk factors are present

10.1016/0891-5849(93)90508-R 35 BulleyS.WrightM.RommensC.YanH.RassamM.Lin-WangK.et al

Cancers (2020) 12:3267